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Int J Vitam Nutr Res. 2007 Jan;77(1):22-33.
B-vitamins and homocysteine in Spanish institutionalized elderly.
Gonzalez-Gross M, Sola R, Albers U, Barrios L, Alder M, Castillo MJ, Pietrzik K.
Grupo Effects 262, Facultad de Medicina, Universidad de Granada, Spain. marcela.gonzalez.gross@upm.es
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Clin Chim Acta. 2007 Feb;376(1-2):150-4. Epub 2006 Aug 11.
Plasma holotranscobalamin compared with plasma cobalamins for assessment of vitamin B12 absorption; optimisation of a non-radioactive vitamin B12 absorption test (CobaSorb).
Hvas AM, Morkbak AL, Nexo E.

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Clin Chem. 2007 Feb;53(2):326-33. Epub 2007 Jan 2.
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
Obeid R, Kostopoulos P, Knapp JP, Kasoha M, Becker G, Fassbender K, Herrmann W.
Department of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, University Hospital of Saarland, Homburg/Saar, Germany.
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Eur J Clin Nutr. 2007 Mar 7; [Epub ahead of print]
Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction.
Aarsetøy H, Valente E, Reine A, Mansoor MA, Grundt H, Nilsen DW.
[1] 1Department of Medicine, Stavanger University Hospital, Stavanger, Norway [2] 5Department of Medicine, University of Bergen, Bergen, Norway.
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Age Ageing. 2007 Mar;36(2):177-83. Epub 2006 Dec 21.
Vitamin B12 deficiency in the aged: a population-based study.
Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL, Pelliniemi TT.
Department of Clinical Chemistry, University of Turku, Turku, Finland. sailalo@utu.fi
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Clin Chem Lab Med. 2007;45(2):197-201.
Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged.
Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL, Pelliniemi TT.
Department of Clinical Chemistry, Turku University Central Hospital, Turku, Finland. sailalo@utu.fi
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Clin Chem. 2007 May;53(5):963-70. Epub 2007 Mar 15.
Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin.
Clarke R, Sherliker P, Hin H, Nexo E, Hvas AM, Schneede J, Birks J, Ueland PM, Emmens K, Scott JM, Molloy AM, Evans JG.
Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom. robert.clarke@ctsu.ox.ac.uk
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Am J Clin Nutr. 2007 Apr;85(4):1057-61.
Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status.
von Castel-Roberts KM, Morkbak AL, Nexo E, Edgemon CA, Maneval DR, Shuster JJ, Valentine JF, Kauwell GP, Bailey LB.
Departments of Food Science and Human Nutrition, University of Florida, Gainesville, USA.
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Clin Chem. 2007 May;53(5):963-70. Epub 2007 Mar 15.
Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin.
Clarke R, Sherliker P, Hin H, Nexo E, Hvas AM, Schneede J, Birks J, Ueland PM, Emmens K, Scott JM, Molloy AM, Evans JG.
Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom. robert.clarke@ctsu.ox.ac.uk
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Epidemiology. 2007 May;18(3):362-6.
Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population.
Ray JG, Wyatt PR, Thompson MD, Vermeulen MJ, Meier C, Wong PY, Farrell SA, Cole DE.
Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. rayj@smh.toronto.on.ca
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J Nutr. 2007 Aug;137(8):1863-7.
Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring.
Murphy MM, Molloy AM, Ueland PM, Fernandez-Ballart JD, Schneede J, Arija V, Scott JM.
Unitat de Medicina Preventiva i Salut Pública, IRCIS, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, 43201 Spain. michelle.murphy@urv.cat
View abstract >

Eur J Clin Nutr. 2007 Jul 4; [Epub ahead of print]
Changes in markers of cobalamin status after cessation of oral B-vitamin supplements in elderly people with mild cobalamin deficiency.
Eussen SJ, Ueland PM, Hiddink GJ, Schneede J, Blom HJ, Hoefnagels WH, van Staveren WA, de Groot LC.
1Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
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Clin Chem Lab Med. 2007 Sep 24; [Epub ahead of print]
Review: Biomarkers of folate and vitamin B(12) status in cerebrospinal fluid.
Herrmann W, Obeid R.
1Department of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, University Hospital of Saarland, Homburg/Saar, Germany.
View abstract >

Am J Clin Nutr. 2007 Nov;86(5):1384-91
Low vitamin B-12 status and risk of cognitive decline in older adults.
Clarke R, Birks J, Nexo E, Ueland PM, Schneede J, Scott J, Molloy A, Evans JG.
Clinical Trial Service Unit, University of Oxford,, University of Oxford, Oxford, United Kingdom; Department of Clinical Biochemistry, AS, Aarhus University Hospital, Aarhus, Denmark.
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Ann Hematol. 2007 Nov 9; [Epub ahead of print]
Measuring holotranscobalamin II, an early indicator of negative vitamin B(12) balance, by radioimmunoassay in patients with ischemic cerebrovascular disease.
Serefhanoglu S, Aydogdu I, Kekilli E, Ilhan A, Kuku I.
Department of Internal Medicine, Turgut Ozal Medical Center, Inonu University, Malatya, Turkey.
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Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2416-2424.
The Association of Gastric Cancer Risk with Plasma Folate, Cobalamin, and Methylenetetrahydrofolate Reductase Polymorphisms in the European Prospective Investigation into Cancer and Nutrition.
Vollset SE, Igland J, Jenab M, Fredriksen A, Meyer K, Eussen S, Gjessing HK, Ueland PM, Pera G, Sala N, Agudo A, Capella G, Del Giudice G, Palli D, Boeing H, Weikert C, Bueno-de-Mesquita HB, Carneiro F, Pala V, Vineis P, Tumino R, Panico S, Berglund G, Ma
Institute of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, 5093 Bergen, Norway. vollset@uib.no.
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Haematologica. 2007 Dec;92(12):1711-2.
Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum.
Aarhus Sygehus, Denmark. almor@as.aaa.dk
Dept. of Clinical Biochemistry, Aarhus University Hospital, Aarhus Sygehus, Denmark. almor@as.aaa.dk
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Clin Chem Lab Med. 2007;45(12):1746-50.
Holotranscobalamin in laboratory diagnosis of cobalamin deficiency compared to total cobalamin and methylmalonic acid.
Obeid R, Herrmann W.
1Department of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, University Hospital of Saarland, Homburg/Saar, Germany.
View abstract >

Clin Chem published January 4, 2008 as doi:10.1373/clinchem.2007.096784
Active B12: A Rapid, Automated Assay for Holotranscobalamin on the Abbott AxSYM Analyzer
Jeff Brady 1, Lesley Wilson 1, Lynda McGregor 1, Edward Valente 1, Lars Orning 2*
1 Axis-Shield Diagnostics, Ltd., Dundee, Scotland, UK
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News

Coming Soon !  The full video recording of the Euromedlab 2007 Active B12 workshop will be available in the next few weeks, register for your copy.

 

Live CME Web Conference on vitamin B12 deficiency, Prof. Ralph Green, Dec 13th 2007, register now.

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Meetings

8-11 December, 2007
American Society of Hematology, Atlanta, booth 544
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