ACTIVE-B12 the next level of vitamin B12 testing

Active-B12 (Holotranscobalamin) is a novel and highly accurate way to assess Vitamin B12 status. An ELISA assay for Active-B12 is now available from Axis-Shield.

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Part Number FMABT100

This is a simple, direct immunoassay for the quantitation of Active-B12 (Holotranscobalamin) in human serum and avoids the need for the various complicated pre-analytical reduction and extraction steps employed by most Total B12 assays, so removing a possible cause of variability.

  • CE-marked and available in 15 languages.
  • 96-well ELISA assay with break-apart strips.
  • Ready-to-use reagents, compatible with liquid-handling automates.
  • Utilises serum or serum-separator tubes
  • Calibrators and controls included
  • Excellent correlation with other commercially-available assays:

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If you are interested in this exciting new test, please contact us or to download our brochure please click here.


Abbott ARCHITECT

In October 2011, Axis-Shield launched the Active-B12 test on Abbott’s flagship ARCHITECT analyser. This assay allows Active-B12 to be tested in high throughput laboratories. In December of 2011, the ARCHITECT assay was granted 510(k) clearance by the FDA and is now available in the USA.


Siemens CENTAUR

Axis-Shield also produces the Active-B12 assay for the Siemens ADVIA CENTAUR platforms. This product is CE-marked and 510(k)-cleared for the USA.