Oxford Project to Investigate Memory and Ageing (OPTIMA)

A team from the Oxford Project to investigate Memory and Ageing (OPTIMA) has found that on average, in those taking vitamin supplements, brain shrinkage slowed by 30%.

In some cases it slowed by more than 50%, making their brain atrophy no worse than that of people without cognitive impairment.

Importantly, only the Active-B12 result and NOT the standard Total B12 result was able to predict the cognitive decline.